Antibiotics Aminosidin (Paromomycin). III. Some Amino Acid Derivatives and Their Biological Activity
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چکیده
منابع مشابه
Synthesis of Some New Bisindole Derivatives and Their Biological Activity
Substituted 1,4-diaza-1,3-butadienes with 2 equivalents of 1,4-naphthoquinone in presence of ethanol or benzene produce corresponding substituted bisindoletetrones via criss-cross cycloaddition reaction. The chemical structure was confirmed by elemental and spectral analysis. Biological activity against some micro-organisms was tested.
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Recently, antimicrobial peptides have been introduced as potent antibiotics with a wide rangeof antimicrobial activities. They have also exhibited other biological activities, including antiinflammatory,growth stimulating, and anti-cancer activities. In this study, an analog of MagaininII was designed and produced as a recombinant fusion protein. The designed sequence containe...
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Recently, antimicrobial peptides have been introduced as potent antibiotics with a wide rangeof antimicrobial activities. They have also exhibited other biological activities, including antiinflammatory,growth stimulating, and anti-cancer activities. In this study, an analog of MagaininII was designed and produced as a recombinant fusion protein. The designed sequence containe...
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Optically pure conjugates of quinolone antibiotics with naturally occurring amino acids are synthesized in 40-98% yields.
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The coupling reaction of benzoic acid and nicotinic acid hydrazides with N- protected L-amino acids including valine, leucine, phenylalanine, glutamic acid and tyrosine is reported. The target compounds, N-Boc-amino acid-(N;-benzoyl)- and N- Boc-amino acid-(N;-nicotinoyl) hydrazides 5a-5e and 6a-6e were prepared in very high yields and purity using N-[(dimethylamino)-1H-1,2,3-triazolo[4,5-b]pyr...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1976
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.96.5_557